联 系 人: 钱经理
电  话: 13636351073
传  真: 86-021-64881400
手  机: 18221656311,13296034073
邮  箱: 2885351131@qq.com
详细地址: 上海市松江区漕河泾汉桥文化科技园B座603
 
首 页 公司简介 产品展示 公司新闻 技术文章 询价留言 联系我们
扫一扫访问手机站扫一扫访问手机站
访问手机站
 
 
 
代理品牌
  ·酶联免疫学类  
  ·分子学类  
  ·生化学类  
ELISA试剂盒
  ·羊elisa试剂盒  
  ·猴elisa试剂盒  
  ·其它类elisa试剂盒  
  ·鹅elisa试剂盒  
  ·鸭elisa试剂盒  
  ·牛elisa试剂盒  
  ·犬ELISA试剂盒  
  ·鸡ELISA试剂盒  
  ·人ELISA试剂盒价格  
  ·大鼠ELISA试剂盒  
  ·小鼠ELISA试剂盒  
  ·进口ELISA试剂盒  
  ·豚鼠ELISA试剂盒  
  ·兔ELISA试剂盒  
  ·猪ELISA试剂盒  
  ·植物ELISA试剂盒  
进口血清
  ·胎牛血清  
  ·人血清  
  ·羊血清  
  ·兔血清  
  ·马血清  
  ·动物血清  
酶联免疫试剂盒
  ·人酶联免疫试剂盒  
  ·大鼠酶联免疫试剂盒  
  ·小鼠酶联免疫试剂盒  
  ·酶联免疫试剂盒价格  
  ·酶联免疫试剂盒批发  
进口标准品
  ·标准品价格  
  ·进口标准品试剂  
进口对照品
  ·对照品试剂  
进口抗体
  ·一抗  
  ·二抗  
食品检测试剂盒
  ·ELISA快速检测试剂盒  
  ·食品与农产品安全速测试剂盒  
  ·其他检测试剂盒  
培养基系列
  ·显色培养基  
  ·大肠杆菌O157培养基  
  ·进口培养基  
生物试剂
  ·氨基酸试剂  
  ·酶试剂  
  ·蛋白质试剂  
  ·抗生素试剂  
  ·其他生化试剂  
  ·植物激素及核酸试剂  
  ·碳水化合物试剂  
  ·色素试剂  
  ·维生素试剂  
  ·缓冲剂试剂  
  ·表面活性剂  
  ·分离材料及耗材  
Spectrum(斯百全)
  ·Spectrum试剂  
金标试剂盒
  ·性病试剂盒  
  ·传染病试剂盒  
  ·染色液试剂盒  
放射免疫诊断试剂盒
  ·甲状腺类试剂盒  
  ·肿瘤类试剂盒  
  ·性腺类试剂盒  
  ·其它类试剂盒  
农药标准品
  ·进口农药标准品  
 
 
 
 

 
点击放大
产品型号:
产品名称:
Rabbit Anti-LC3 antibody
产品报价:
产品特点:
自噬微管相关蛋白轻链3抗体研究领域 :肿瘤 细胞生物 神经生物学 信号转导 细胞骨架 细胞外基质 细胞自噬
  Rabbit Anti-LC3 antibody的详细资料:

英文名称: LC3
中文名称: 自噬微管相关蛋白轻链3抗体
别    名: Autophagy related protein LC3 A; Autophagy related protein LC3 B; Autophagy related ubiquitin like modifier LC3 A; Autophagy related ubiquitin like modifier LC3 B; MAP1 light chain 3 like protein 1; MAP1 light chain 3 like protein 2; MAP1A/1B light chain 3 A; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1ALC3; MAP1BLC3; MAP1LC3A; MAP1LC3B; Microtubule associated protein 1 light chain 3 alpha; Microtubule associated protein 1 light chain 3 beta; Microtubule associated proteins 1A/1B light chain 3; Microtubule associated proteins 1A/1B light chain 3A; Microtubule associated proteins 1A/1B light chain 3B; MLP3A_HUMAN.  
研究领域 :肿瘤  细胞生物  神经生物学  信号转导  细胞骨架  细胞外基质  细胞自噬  
抗体来源 :Rabbit
克隆类型: Polyclonal
交叉反应: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, Goat, 
产品应用 :WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量: 14/16kDa
细胞定位 :细胞浆 
性    状: Lyophilized or Liquid
浓    度: 1mg/ml
免 疫 原 :KLH conjugated synthetic peptide derived from human LC3:31-121/121 
亚    型 :IgG
纯化方法 :affinity purified by Protein A
储 存 液 :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 :Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 :background:
A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.
Function:
Probably involved in formation of autophagosomal vacuoles (autophagosomes). 
Subunit:
3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. Interacts with SQSTM1. Interacts with TP53INP1 and TP53INP2. 
Subcellular Location:
Cytoplasmic. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note: LC3B binds to the autophagic membranes.
Tissue Specificity:
Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.
Post-translational modifications:
The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. 
Similarity:
Belongs to the MAP1 LC3 family.

产品相关关键字: Rabbit Anti-LC3 antibody
 如果你对Rabbit Anti-LC3 antibody感兴趣,想了解更详细的产品信息,填写下表直接与厂家联系:

留言框

  • 产品:

  • 留言内容:

  • 您的单位:

  • 您的姓名:

  • 联系电话:

  • 常用邮箱:

  • 详细地址:

  • 省份:

  • 验证码:

    请输入计算结果(填写阿拉伯数字),如:三加四=7
 相关同类产品:
HycloneRPML Medium Modified 1640  Hyclone双抗Sv30010.01 
Rabbit Anti-LC3 antibody 
 

 

上海沪鼎生物科技有限公司 版权所有 总访问量:192122 地址:上海市松江区漕河泾汉桥文化科技园B座603 邮编:201615
电话:13636351073 传真:86-021-64881400 手机:18221656311,13296034073 联系人:钱经理 邮箱:2885351131@qq.com
GoogleSitemap 网址:www.shhdsj.com 技术支持:化工仪器网 管理登陆 ICP备案号:沪ICP备13029363号-1

主营产品:ELISA试剂盒,生物试剂,培养基,血清,抗体,细胞等

电话
021-60537722
021-60520348
传真
86-021-64881400
手机
13636351073
18221656311
13296034073
13296070348

化工仪器网

推荐收藏该企业网站